Welcome to my homepage

Biography

Dr Laia Pasquina Lemonche

I am a Research Associate in Professor Jamie Hobbs’ group at University of Sheffield. I graduated from Physics at the Autonomous University of Barcelona (UAB) in 2015Then, I received a ster in Nanobiotechnology and Nanoscience UAB. Then, I started her PhD in Biophysics at the University of Sheffield focused on deciphering the molecular architecture of gram-positive bacterial cell wall using AFM (L.Pasquina-Lemonche, J.Burns, et al, 2020, Nature). After my PhD finished in August 2020, I keep working in the Hobbs group focusing on understanding how the bacterial cell wall structure changes upon antibiotic treatments and other environments. Recently, I am developing new approaches to push the limits of resolution of biological material with AFM with the aim to study the peptidoglycan architecture of the cell wall more in detail.

Research interests

My interests are the following:

• Using the imaging power of Atomic Force Microscopy (AFM) to interrogate biological samples
• Pushing the limits of resolution of current AFM methodologies to their limit
• Architecture and organisation of the bacterial cell wall (peptidoglycan) and other cell envelopes
• How does the architecture of the cell wall interacts with the function of the cell envelope for cell viability
• Using and developing image analysis softwares and pushing for open source coding and publication

Example of some of the imaging analysis that I am currently developing:

![image] (https://github.com/Laia-Pasquina/Git_lesson_RSE/blob/7b8bccd0e449eeae105bbf14eccb2cc84fc5f5b4/group%20of%20pores.gif)